Former Celtic youngster Mark Fotheringham signed for Norwich on January 31st 2007. Dundee-born Fotheringham was a free agent and had been training with Rangers since he quit Swiss club Aarau, but the Glasgow giants were unable to offer him first-team football, paving the way for him to move to Carrow Road. He signed until the end of the 2006/7 season with an option for an additional year.

Fotheringham played three times for Celtic, graduating from the youth ranks at Parkhead. In 2003, he moved to his hometown Dundee F.C.. After two years with the Dark Blues making 51 appearances and scoring 4 goals, Fotheringham moved to Germany with SC Freiburg, where he played for a season. Fotheringham moved to Swiss side FC Aarau in 2006 but left midway through the season.

Fotheringham is known for his trademark "Fozzy Flick", a move involving flicking the ball high over his - and his opponents head - then running round them and regaining possession.

He made his City debut in the 2-1 home win over Leeds United on 3rd February 2007 and finished the season with 15 goals and a one year extension to his contract.

He scored his first goal for Norwich in the 5-2 Carling Cup first round victory over Barnet on 14th August 2007.

Mark was named club captain when Glenn Roeder took over as Norwich manager

In early May 2008, the BBC reported that Charlton were preparing a move for Fotheringham as Charlton manager Alan Pardew needs a long term replacement for departed midfielder Andy Reid

Following a disagreement with manager Bryan Gunn when substituted during Norwich's defeat to Coventry on 28th February 2009, Fotherington was linked with a loan move to Preston. He also had the captaincy removed from him. He did not play again for Norwich and was released from his contract at the end of April 2009. He was linked initially with a move to Coventry City and then at the end of May with Blackpool and Spanish sides Espanyol and Mallorca. He was also invited to train with Nigel Clough's Derby County. He later had a brief trial with Sheffield United.

Mark signed for Dundee United on 24th September 2009 on a short term contract until January 2010 when he will sign for Cypriot side Anorthosis Famagusta. He made just three appearances before he moved to Cyprus.

In June 2011, Mark was linked with a move to Coventry City. He was also banned from training with Anorthosis Famagusta by Bulgarian boss Stanimir Stoilov

In September 2011, reports suggesting that Mark was training with Sheffield United were dismissed by Blades manager Danny Wilson

On 13th October 2011, Fotheringham and former Rangers defender Maurice Ross signed for Scottish side Livingston until January 2012. This was extended until the end of January 2012.

He had a brief trial at Wolverhampton Wanderers in January 2012, but was not offered a contract. On 7th March 2012 Fotheringham re-joined Dundee but on 30th April 2012 it was announced his contract would not be renewed.

On 9th July 2012, it was reported that Fotheringham was on trial at German side Hoffenheim. "We have decided to extend his trial," manager Markus Babbel told spox.com. "Mark made a good impression during his first two weeks and he did impress. He is also a lad who is settling in well off the pitch. We have come to the conclusion that we will continue to monitor him as a potential signing." He spent eight weeks on trial at Hoffenheim before trialling with Wolfsburg.

At the end of July 2012, Fotheringham trialled for Steve Bruce's Hull City but following a friendly defeat at Doncaster, the Tigers' interest was quelled.

On 13th September 2012, Fotheringham joined Ross County. After making thirteen appearance, Fotheringham left Ross County to join Swiss side Luzern on trial in June 2013. On 23rd July 2013 Fotheringham joined Notts County.

Fotheringham was surprisingly signed by Championship side Fulham on 8th August 2014 following a successful trial. He made his debut on 20th August in the 1-0 defeat to Wolves. He was released by the Cottagers on 31st January 2015 having made just three appearances.

In February 2015, he joined Hibs on trial.

On 5th January 2016, he signed for Livingston until the end of the 2015/16 season

In July 2016, he signed a three year contract as assistant manager of German side Karlsruher SC whose manager Tomas Oral, knew Fortheringham from his time at Fulham, where Oral was assistant to Felix Magath. Fortheringham said “He (Oral) tells me he saw something in me from the start at that club. I was first in the door at the training ground every morning and the last out in the afternoon, and, as an experienced player, I took my responsibilities very seriously. I wanted to set an example for the younger guys – and I think I did that. When I got the call about coming to Germany this summer, it was a wee bit out of the blue. I’m doing my B Licence at the moment, and when I spoke to the guys at the SFA, they told me it was a no-brainer. Tomas and the sporting director at Karlsruher, Jens Todt, have shown real faith in me. But I believe in my ability, and I believe I can repay them. I see coaching as a really good area for me, with my knowledge of the game, my attitude towards hard work, and my experience.” Karlsruher are hoping for promotion to the Bundesliga after an eight year absence

In 2017, he was appointed player / assistant manager of Scottish side Cowdenbeath.

On 2nd April 2019 he returned to Germany to join the coaching staff at FC Ingolstadt managed by Tomas Oral. The team left the club on 30th June 2019. When their replacement Jeff Saibene was sacked in March 2020, Oral and Fortheringham were invited back to their previous roles. Despite leading Ingolstadt to promotion via the play-offs against Osnabruck, the pair quit on 3rd June 2021 when Oral couldn't agree terms on an extended deal.

On 19th March 2022 it was reported that Fotheringham had joined Hertha Berlin as assistant to Felix Magrath. He managed the relegation strugglers in their clash with Hoffenhim when Magrath tested positive with Covid-19. He said “It's not an easy situation but my focus is just what we can do on the pitch this weekend. We did good sessions, I'm very happy with that. There's a good mix of young and experienced players in the team, which is important. They were wide awake to everything we prepared. Now we have to put that on the pitch – we want to get those three points for Hertha. We had a clear idea in the coaching staff of what we wanted to do and achieve this week. It's important that we convert the good training work into conviction, which we also see on the pitch on Saturday."

At the end of September 2022 he was strongly linked with the managerial vacancy at Huddersfield. His appointment as their Head Coach was confirmed on 28th September 2022 on a deal lasting until 2025. Fotheringham will be assisted by coaches Narcis Pelach and Paul Harsley - who had been in caretaker change after Schofield's sacking - and other existing technical staff.

Fotheringham was sacked on 8th February 2023 after only winning five of his 21 games in charge. He was only in the role for 134 days. The sacking came after Huddersfield's 2-2 draw with 10 men Blackpool.

In January 2024 he was appointed as part of Jurgen Klinsman's coaching team for South Korea ahead of the Asian Cup 2024. Fotheringham had developed a relationship with Klinsmann during his time in Germany. Klinsmann and team were sacked following South Korea's exit at the semi-final stage amid criticism of Klinsmann's leadership. Fotheringham then undertook an interview questioning why he and other Scottish coaches were overlooked for manager roles at clubs like Aberdeen, Hibs and Hearts.