Arturo Lupoli joined Norwich City on loan from Italian side Fiorentina on 22nd July 2008.

Lupoli began his footballing career as a youth with Italian side Parma. During his Under-17 season he scored 45 goals in 22 games, one of the best tallies ever recorded in Italian youth history. However, in 2004 he signed a scholarship contract with Arsenal. The Gunners repaid Parma with £200,000 compensation.

He made his debut for Arsenal on 27 October 2004 against Manchester City in the Carling Cup, an then scored two goals in the following round against Everton.He scored prolifically for the youths and reserves but made only one appearance in the Premiership.

Lupoli moved to Derby County on a season-long loan on August 18, 2006, and debuted for Derby in the 0-0 draw at home to Norwich City the following day. He then got a brace against Colchester United in a game which Derby lost 4-3. On January 6, 2007, Lupoli scored Derby County's first hat-trick for over a decade in a 3-1 victory third round FA Cup tie against Wrexham.

On February 26th 2007, he signed a pre-contract with Fiorentina despite interest from the 2 Milan clubs and Napoli. During the 2007/8 season, he was loaned out to Treviso for whom he made 16 appearances but failed to score.

He made his Norwich debut in the 2-0 defeat at Coventry City on the opening day of the 2008/9 season. Hs first goals came in the 2-2 draw at Cardiff on 23rd August 2008 when he scored twice. At the end of November 2008, he was linked with a move to Wigan with Southampton also keen on him.

On 2nd February 2009, Norwich terminated the loan deal with Fiorentina with the agreement of all parties. He had started just threegames since mid-September and seemed to be out of new manager Bryan Gunn's plans. Gunn said: “We wish Arturo all the best. He's been frustrated with the lack of chances he has had to start games and we had a chat last week and discussed the options which were suitable for him. He's been a hero among City fans, with the goals he has scored for us and when he ran up to them after his goal at Charlton. I know he's been frustrated with the lack of chances but after we signed Chris Killen and Alan Gow, he now feels further down the pecking order and we wish him well for the future.” Lupoli was then loaned to Sheffield United for the remainder of the 2008/9 season.

Returning to Italy, he was sold to Ascoli on 25th June 2009 with midfielder Francesco Di Tacchio going the other way

After 66 appearances and 11 goals for Ascoli, he joined U.S. Grosseto in 2011. In July 2013, after two years, 45 appearances and eight goals at Grosseto, Lupoli moved to another Serie B team on a free transfer, this time Varese. He left Varese on 21st February 2014, to join Hungarian side Honved on loan.

On 2nd February 2015, he signed for Italian side Frosinone helping them to promotion to Serie A. On 31st August 2015, he returned to Serie B signing for AC Pisa. On 1st February 2016, he was loaned to Catania who play in the third tier of Italian football

On 27th January 2017, he moved to FC SudTirol, his tenth Italian club. They are based in Bolzano and play in Lega Pro, the Italian regional third tier with Sudtirol playing in Group B (North & Central West). He moved to their league rival Fermana on 31st August 2017.

He moved to Virtus Verona on 19th July 2019 and then to Montegiorgio on 10th October 2020 (they play in Serie D, Group F). In August 2021, he joined Borgo San Donnino in Serie D.

He has been capped at Italian Under-21 level.