Mike Sheron was signed for Norwich from Manchester City on the 26th August 1994. A Maine Road youth team product, Mike spent three successful seasons in Manchester playing 100 league matches scoring 24 times. He also acquired eleven England U-21 caps. His career failed to blossom at Carrow Road and he was beset with injuries. In 28 first team matches for Norwich, he scored just twice.

In October 1995, he joined Stoke City in exchange for Keith Scott. The move to the Victoria Ground kickstarted the talent and promise he had shown at Maine Road. In his first season, he scored fifteen times in 28 league appearances and as of March 23rd 1997 had added another 21goals (in league and cup) to this tally. His phenomenal goalscoring rate attracted the attention of other clubs including West Ham, Everton and QPR. The latter of these secured his signature on July 1st 1997 for £2.5million. Competition from Birmingham City was overwhelmed by QPR's personal terms - an almost £1million signing on fee and approximately £5000 a week in wages. Norwich received £700,000 as a sell-on clause had been included in the initial exchange of Sheron to Stoke.

As transfer deadline day approached on 26th March 1998, Mike was linked by Yahoo's Teamtalk with moves to West Bromwich Albion (a swap for Andy Hunt) and to his first club Manchester City. QPR were rumoured to be circulating his name in the hope of raising some funds by selling Sheron who did not fit into Ray Harford's plans at QPR. Teamtalk reported in mid-September 1998 that he was for sale at a cut-down £1.1million and that both Sheffield Wednesday and Norwich were interested. According to the Daily Mirror, Mike Sheron was to rejoin Manchester City albeit on loan. Supposedly City manager Joe Royle contacted QPR boss Ray Harford about the possibility of such a deal. Bradford were also linked with Sheron according to the Evening Standard

Despite regaining his scoring form under new manager Gerry Francis, Mike joined Barnsley on 27th January 1999 for £1.5million, replacing Ashley Ward who joined Blackburn from Barnsley over Christmas. QPR chairman Chris Wright explained the transfer stating that Mike was on a Premiership scale salary of around £10,000 a week. By letting him go, QPR could afford to bring up to four more players to Loftus Road.

In February 2001, it was suggested that Barnsley manager Nigel Spackman would quickly move to free Sheron who was not earning his keep at Oakwell. The 2001 pre-season saw Mike linked with a move to Blackpool where he would team up again with Steve McMahon. This did not materialise but when Sheron was given a free transfer by Barnsley in May 2003, he was immediately linked with a move to Blackpool again. This indeed came true with Sheron signing a one year deal with Blackpool at the end of July 2003.

Released at the end of the 2003/4 season, Mike joined Chester City on trial in July 2004. The unrest at the Deva Stadium following manager Mark Wright's departure in August 2004 persuaded Mike to seek a career elsewhere and he signed for Macclesfield. Macclesfield released Sheron in March 2005. Despite interest from Scarborough, he signed for Shrewsbury until the end of the 2004/5 season when the Shrews decided that they would not keep him on.

On 20th October 2005, Unibond Northern League first division side Warrington Town announced that they had signed Sheron. In Decmber 2005, he abandoned his playing career to concentrate on coaching for Warrington.

Mike joined Bury as youth team coach during the summer of 2007.

After coaching briefly at Oldham (2010-11), Bath University (2011) and Liverpool's Academy (2011-13), Sheron was appointed Head of Academy Coaching at Rotherham on 17th September 2013. In March 2015 he left Rotherham and joined Blackburn Rovers as Professional Development Phase Assistant Coach